Nanocrystal is widely applied to improve the dissolution of poorly water-soluble drugs.We aimed to prepare meloxicam (MLX) nanocrystals using the bead mill method, followed by high-pressure homogenization (HPH).Simple drying at room temperature (RD), vacuum-drying (VD), and freeze-drying (FD) using mannitol or trehalose as a cryoprotectant were app
Ellipse center extraction is the important basis of camera calibration with circle arrays calibration board, which directly affects the measurement accuracy of machine vision system.Aiming at the problem of high noise sensitivity of the most ellipse center extraction methods, a high robust multi-ellipse center extraction method is proposed.The idea
Conodonts from the type region of the Oandu Regional Stage (Katian, Upper Ordovician) in NE Estonia were studied.Here, the lower boundary of the stage corresponds to a discontinuity surface at the base of gotrax rear fender the Hirmuse Formation and, in conodont succession, is marked by the disappearance of Semiacontiodus sp.and Besselodus? sp.The